Evaluation of the impact of memantine treatment initiation on psychotropics use: a study from the French national health care database

JS Vidal, JM Lacombe, JF Dartigues, F Pasquier… - …, 2008 - karger.com
Background: Clinical studies reported that treatments for Alzheimer's disease may have an
impact on behavioral and psychiatric disorders. We tested the hypothesis that memantine
treatment initiation modifies psychotropic medication in real-life practice patients. Methods: A
2-year follow-up cohort study was performed. A sample of patients treated in the general
population, extracted from the database of the French national healthcare system (CNAM-
TS), was examined. The sample included 4,600 memantine-treated patients (mean age 79.8 …
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